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DNDI-5561

Chemical Structure : DNDI-5561

CAS No.:

DNDI-5561 (DNDi-5561, DNDI 5561)

Catalog No.: PC-25290Not For Human Use, Lab Use Only.

DNDI-5561 is a small molecule inhibitor of T. cruzi and L. infantum with IC50 of 38 uM and 0.2 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DNDI-5561 is a small molecule inhibitor of T. cruzi and L. infantum with IC50 of 38 uM and 0.2 uM.

Physicochemical Properties

M.Wt 445.45
Formula C21H22F3N7O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-N-(4-cyclopropyl-3-(pyridin-2-yl)-1H-pyrazol-5-yl)-3-((4-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)pyrrolidine-1-carboxamide

References

1. Abdulai Z, et al. ACS Infect Dis. 2025 Aug 11. doi: 10.1021/acsinfecdis.5c00481.

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