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DNDI-VL-2098

Chemical Structure : DNDI-VL-2098

CAS No.: 681492-17-1

DNDI-VL-2098

Catalog No.: PC-25292Not For Human Use, Lab Use Only.

DNDI-VL-2098 is an orally effective preclinical drug candidate for visceral leishmaniasis (VL) with IC50 of 0.17 uM for L. infantum.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DNDI-VL-2098 is an orally effective preclinical drug candidate for visceral leishmaniasis (VL) with IC50 of 0.17 uM for L. infantum.

Physicochemical Properties

M.Wt 359.26
Formula C14H12F3N3O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-methyl-6-nitro-2-((4-(trifluoromethoxy)phenoxy)methyl)-2,3-dihydroimidazo[2,1-b]oxazole

References

1. Mukkavilli R, et al. Eur J Pharm Sci. 2014 Dec 18;65:147-55.

2. Thompson AM, et al. J Med Chem. 2016 Mar 24;59(6):2530-50.

3. Gupta S, et al. J Antimicrob Chemother. 2015 Feb;70(2):518-27.

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