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DNMT3B inhibitor 33h

Chemical Structure : DNMT3B inhibitor 33h

CAS No.: 2561412-48-2

DNMT3B inhibitor 33h

Catalog No.: PC-72247Not For Human Use, Lab Use Only.

DNMT3B inhibitor 33h is a selective, small molecule inhibitor of DNMT3B with IC50 of 4.8 uM in DRONE assays.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    DNMT3B inhibitor 33h is a selective, small molecule inhibitor of DNMT3B with IC50 of 4.8 uM in DRONE assays.

    Physicochemical Properties

    M.Wt 460.516
    Formula C22H20N8O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-(3-(6-amino-9H-purin-8-yl)phenyl)-N-methyl-N-((4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)methyl)propanamide

    References

    1. Ana S Newton, et al. ACS Med Chem Lett. 2020 Feb 7;11(5):971-976.

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