Chemical Structure : DS-3032 tosylate hydrate
CAS No.:
2095625-97-9
DS-3032 tosylate hydrate
(Milademetan tosylate hydrat, DS-3032b)
Catalog No. : PC-21238Not For Human Use, Lab Use Only.
Milademetan (DS-3032b) is a potent, selective, orally available MDM2-p53 inhibitor with potential antineoplastic activity.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2123801
Biological Activity
Milademetan (DS-3032b) is a potent, selective, orally available MDM2-p53 inhibitor with potential antineoplastic activity.
Physicochemical Properties
M.Wt
790.73
Formula
C37H42Cl2FN5O7S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(3'R,4'S,5'R)-N-((3R,6S)-6-carbamoyltetrahydro-2H-pyran-3-yl)-6''-chloro-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamide 4-methylbenzenesulfonate
References
1. Ishizawa J, et al. Cancer Res. 2018 May 15;78(10):2721-2731.
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