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Chemical Structure : DS08701581
Catalog No.: PC-22693Not For Human Use, Lab Use Only.
DS08701581 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase with IC50 of 0.32 nM, shows in vivo antitumor efficacy.
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DS08701581 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase with IC50 of 0.32 nM, shows in vivo antitumor efficacy.
DS08701581 shows potent cell-free and cell activities in this template, good oral BA, and improved kinase selectivity, resulting in significant tumor growth inhibition in the Ba/F3-FER tumor model without body weight loss.
| M.Wt | 488.60 | |
| Formula | C26H32N8O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Toru Taniguchi, et al. ACS Med Chem Lett. 2024 Jun 13;15(7):1010-1016.
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