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DS21360717

Chemical Structure : DS21360717

CAS No.: 2304654-43-9

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DS21360717 (DS 21360717)

Catalog No.: PC-22694Not For Human Use, Lab Use Only.

DS21360717 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase tyrosine kinase with IC50 of 0.49 nM, shows in vivo antitumor efficacy.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DS21360717 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase tyrosine kinase with IC50 of 0.49 nM, shows in vivo antitumor efficacy.

Physicochemical Properties

M.Wt 389.46
Formula C21H23N7O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

7-(((1R,2S)-2-aminocyclohexyl)amino)-4-oxo-5-(m-tolylamino)-3,4-dihydropyrido[3,4-d]pyridazine-8-carbonitrile

References

1. Taniguchi T, et al. ACS Med Chem Lett. 2019 Mar 15;10(5):737-742.

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