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DS28120313

Chemical Structure : DS28120313

CAS No.: 2146177-09-3

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DS28120313 (DS 28120313)

Catalog No.: PC-22678Not For Human Use, Lab Use Only.

DS28120313 is a potent orally active hepcidin production inhibitor with IC50 of 93 nM (hepcidin mRNA expression), shows serum hepcidin-lowering effects.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DS28120313 is a potent orally active hepcidin production inhibitor with IC50 of 93 nM (hepcidin mRNA expression), shows serum hepcidin-lowering effects.

Physicochemical Properties

M.Wt 311.35
Formula C16H17N5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

methyl [6-(3-cyclopropyl-5-methyl-1H-pyrazol-4-yl)-1H-indazol-4-yl]carbamate

References

1. Takeshi Fukuda, et al. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5252-5257.

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