DS79540454

Chemical Structure : DS79540454

Catalog No.: PC-25776Not For Human Use, Lab Use Only.

DS79540454 is a potent hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitor with IC50 of 0.26 uM for HIF-PHD2.

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Biological Activity

DS79540454 is a potent hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitor with IC50 of 0.26 uM for HIF-PHD2.

M.Wt	420.43
Formula	C22H20N4O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((5-(([1,1'-biphenyl]-3-ylmethyl)carbamoyl)-4-hydroxypyrimidin-2-yl)amino)-4-oxobutanoic acid

1. Fukuda T, et al. Bioorg Med Chem Lett. 2025 Nov 19;131:130476.