DS88790512 |CAS: 2231089-95-3 Probechem Biochemicals

Chemical Structure : DS88790512

DS88790512 (DS 88790512;DS-88790512)

Catalog No.: PC-35044Not For Human Use, Lab Use Only.

DS88790512 is a potent, selective, and orally bioavailable TRPC6 blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).

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Biological Activity

DS88790512 is a potent, selective, and orally bioavailable TRPC6 blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).

Physicochemical Properties

M.Wt	367.493
Formula	C22H29N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(((1R,3aR,7aS)-2-((R)-3-aminopiperidin-1-yl)-7a-methyl-5-oxooctahydro-1H-inden-1-yl)oxy)benzonitrile

References

1. Motoyama K, et al. Bioorg Med Chem Lett. 2018 Mar 22. pii: S0960-894X(18)30251-8.

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DS88790512 (DS 88790512;DS-88790512)

Biological Activity

Physicochemical Properties

References

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