DSM186 | AbDHODH inhibitor | Probechem Biochemicals

Chemical Structure : DSM186

DSM186 (DSM 186)

Catalog No.: PC-49850Not For Human Use, Lab Use Only.

DSM186 (DSM 186) is a high potent A. baumannii DHODH (AbDHODH) inhibitor with IC50 of 28 nM, has MIC <1 ug/mL against geographically diverse A. baumannii strains, including meropenem-resistant isolates.

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Biological Activity

DSM186 (DSM 186) is a high potent A. baumannii DHODH (AbDHODH) inhibitor with IC50 of 28 nM, has MIC <1 ug/mL against geographically diverse A. baumannii strains, including meropenem-resistant isolates.

Physicochemical Properties

M.Wt	350.31
Formula	C13H11F5N4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-methyl-N-(4-(pentafluoro-l6-sulfaneyl)phenyl)imidazo[1,2-a]pyrimidin-5-amine

References

1. Russo TA, et al. Proc Natl Acad Sci U S A. 2022 Dec 20;119(51):e2213116119.

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DSM186 (DSM 186)

Biological Activity

Physicochemical Properties

References

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