Chemical Structure : DSM265
CAS No.:
1282041-94-4
DSM265
(DSM-265;DSM 265)
Catalog No. : PC-60458Not For Human Use, Lab Use Only.
DSM265 is a potent, highly selective, long-duration and orally bioavailable malaria DHODH (PfDHODH) inhibitor with IC50 of 0.01 ug/mL.
Packing Price Stock Quantity 5 mg $78 In stock 0 1 2 3 4 5 10 mg $118 In stock 0 1 2 3 4 5 25 mg $218 In stock 0 1 2 3 4 5 50 mg $358 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6045801
Biological Activity
DSM265 is a potent, highly selective, long-duration and orally bioavailable malaria DHODH (PfDHODH ) inhibitor with IC50 of 0.01 ug/mL.
Physicochemical Properties
M.Wt
415.334
Formula
C14H12F7N5S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-(1,1-Difluoroethyl)-5-methyl-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
References
1. Coteron JM, et al. J Med Chem.
2. Phillips MA, et al. Sci Transl Med.
3. Kokkonda S, et al. J Med Chem.
4. Phillips MA, et al. ACS Infect Dis.
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