DT-0111 | P2X2/3 antagonist | Probechem Biochemicals

Chemical Structure : DT-0111

DT-0111 (DT0111)

Catalog No.: PC-20742Not For Human Use, Lab Use Only.

DT-0111 (DT0111) is a selective and effective, water-soluble antagonist at P2X2/3R, does not activate or block P2YR, inhibits ATP-induced current in nodose ganglionic cells with IC50 of 0.3 uM.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

DT-0111 (DT0111) is a selective and effective, water-soluble antagonist at P2X2/3R, does not activate or block P2YR, inhibits ATP-induced current in nodose ganglionic cells with IC50 of 0.3 uM.
DT-0111 markedly inhibited the activation by ATP of nodose pulmonary vagal afferents in vitro.
DT-0111 inhibited aerosolized ATP-induced bronchoconstriction and cough in vivo.

Physicochemical Properties

M.Wt	670.36
Formula	C19H25N6O15P3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

References

1. Amir Pelleg, et al. Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619877960.

2. Patent US 11440935.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

DT-0111 (DT0111)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.