Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : DT-0111
Catalog No.: PC-20742Not For Human Use, Lab Use Only.
DT-0111 (DT0111) is a selective and effective, water-soluble antagonist at P2X2/3R, does not activate or block P2YR, inhibits ATP-induced current in nodose ganglionic cells with IC50 of 0.3 uM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
DT-0111 (DT0111) is a selective and effective, water-soluble antagonist at P2X2/3R, does not activate or block P2YR, inhibits ATP-induced current in nodose ganglionic cells with IC50 of 0.3 uM.
DT-0111 markedly inhibited the activation by ATP of nodose pulmonary vagal afferents in vitro.
DT-0111 inhibited aerosolized ATP-induced bronchoconstriction and cough in vivo.
| M.Wt | 670.36 | |
| Formula | C19H25N6O15P3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Amir Pelleg, et al. Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619877960.
2. Patent US 11440935.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
