DUSP6 inhibitor BCI |CAS:1245792-51-1 Probechem Biochemicals

Chemical Structure : DUSP6 inhibitor BCI

CAS No.: 1245792-51-1

DUSP6 inhibitor BCI (NSC-150117, NSC150117)

Catalog No.: PC-60183Not For Human Use, Lab Use Only.

BCI (NSC150117) is a small-molecule, allosteric inhibitor of DUSP6 (dual-specificity phosphatase 6) with IC50 of 12.3 uM.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$188	In stock
25 mg	$298	In stock
50 mg	$488	In stock
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Biological Activity

BCI (NSC150117) is a small-molecule, allosteric inhibitor of DUSP6 (dual-specificity phosphatase 6) with IC50 of 12.3 uM.
BCI (NSC150117) also inhibits human DUSP1 with IC50 of 11.5 uM.
BCI (NSC150117) suppresses the ERK-induced activation of Dusp6 and regulates heart size in zebrafish.

Physicochemical Properties

M.Wt	317.43
Formula	C22H23NO
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one

References

1. Molina G, et al. Nat Chem Biol. 2009 Sep;5(9):680-7.

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DUSP6 inhibitor BCI (NSC-150117, NSC150117)

Biological Activity

Physicochemical Properties

References

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