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Chemical Structure : DUSP6 inhibitor BCI
CAS No.: 1245792-51-1
Catalog No.: PC-60183Not For Human Use, Lab Use Only.
BCI (NSC150117) is a small-molecule, allosteric inhibitor of DUSP6 (dual-specificity phosphatase 6) with IC50 of 12.3 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $488 | In stock | |
| 100 mg | Get quote |
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BCI (NSC150117) is a small-molecule, allosteric inhibitor of DUSP6 (dual-specificity phosphatase 6) with IC50 of 12.3 uM.
BCI (NSC150117) also inhibits human DUSP1 with IC50 of 11.5 uM.
BCI (NSC150117) suppresses the ERK-induced activation of Dusp6 and regulates heart size in zebrafish.
| M.Wt | 317.43 | |
| Formula | C22H23NO | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one |
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1. Molina G, et al. Nat Chem Biol. 2009 Sep;5(9):680-7.
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