DW-3-15

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Chemical Structure : DW-3-15

Catalog No.: PC-27143Not For Human Use, Lab Use Only.

DW-3-15 is a praziquantel and artesunate conjugate and effective anti-schistosomal agent, inhibits both juvenile and adult Schistosoma japonicumin through SjHAT1 inhibition, exhibits good worm killing activity both in vitro and in vivo.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	694.82
Formula	C38H50N2O10
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(cyclohexanecarbonyl)-4-oxo-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinolin-10-yl ((3R,5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl) succinate

References

1. Dong L, et al. PLoS One. 2014 Nov 11;9(11):e112163.

2. Wang X, et al. Parasit Vectors. 2019 May 3;12(1):199.

3. Duan WW, et al. Bioorg Med Chem Lett 22: 1587–1590.

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DW-3-15

Biological Activity

Physicochemical Properties

References

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