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Chemical Structure : DZ2002
CAS No.: 33231-14-0
Catalog No.: PC-45486Not For Human Use, Lab Use Only.
DZ2002 is a potent, reversible type III inhibitor of SAHH (S-adenosyl-L-homocysteine hydrolase) with Ki of 17.9 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $238 | In stock | |
| 10 mg | $388 | In stock | |
| 25 mg | $598 | In stock | |
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| 100 mg | Get quote |
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DZ2002 is a potent, reversible type III inhibitor of SAHH (S-adenosyl-L-homocysteine hydrolase) with Ki of 17.9 nM.
DZ2002 is more effectively than type I inhibitor DHCaA with greatly reduced cytotoxicity.
DZ2002 significantly reduces both a mixed lymphocyte reaction and IL-12 production from in vitro-stimulated splenocytes.
DZ2002 suppresses a delayed-type hypersensitivity reaction and antibody secretion in vivo.
| M.Wt | 251.2419 | |
| Formula | C10H13N5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 61 mg/mL |
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| Chemical Name/SMILES |
9H-Purine-9-butanoic acid, 6-amino-α-hydroxy-, methyl ester |
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1. Wu QL, et al. J Pharmacol Exp Ther. 2005 May;313(2):705-11.
2. Fu YF, et al. J Pharmacol Exp Ther. 2006 Mar;316(3):1229-37.
3. Kominsky DJ, et al. J Immunol. 2011 Jun 1;186(11):6505-14.
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