Chemical Structure : Danirixin
CAS No.:
954126-98-8
Danirixin
(GSK-1325756, GSK1325756)
Catalog No. : PC-45710Not For Human Use, Lab Use Only.
Danirixin (GSK1325756) is a high-affinity, selective and reversible CXCR2 antagonist (IC50=12.5 nM, CXCL8.
Packing Price Stock Quantity 5 mg $148 In stock 0 1 2 3 4 5 10 mg $228 In stock 0 1 2 3 4 5 25 mg $398 In stock 0 1 2 3 4 5 50 mg $598 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4571001
Biological Activity
Danirixin (GSK1325756) is a high-affinity, selective and reversible CXCR2 antagonist (IC50=12.5 nM, CXCL8.
Physicochemical Properties
M.Wt
441.9041
Formula
C19H21ClFN3O4S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: 8 mg/mL
Chemical Name/SMILES
Urea, N-[4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl]-N'-(3-fluoro-2-methylphenyl)-
References
1. Bloomer JC, et al. Eur J Pharm Biopharm
2. Miller BE, et al. BMC Pharmacol Toxicol
3. Busch-Petersen J, et al. J Pharmacol Exp Ther
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