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Darirestat

Chemical Structure : Darirestat

CAS No.: 957051-88-6

Darirestat (WJ-38)

Catalog No.: PC-22473Not For Human Use, Lab Use Only.

WJ-38 (Darirestat) is a small molecule aldose reductase (AR) inhibitor, does not affect AR protein expression, reduces oxidative stress by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

WJ-38 (Darirestat) is a small molecule aldose reductase (AR) inhibitor, does not affect AR protein expression, reduces oxidative stress by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.

Physicochemical Properties

M.Wt 392.23
Formula C19H15Cl2NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1(4H)-Quinolineacetic acid, 3-[(2,3-dichlorophenyl)methyl]-6-methoxy-4-oxo-

References

1. Yang L, et al. Eur J Pharmacol. 2024 Mar 15;967:176376.

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