Darirestat (WJ-38)

Chemical Structure : Darirestat

Catalog No.: PC-22473Not For Human Use, Lab Use Only.

Darirestat (WJ-38) is a small molecule aldose reductase (AR) inhibitor, does not affect AR protein expression, reduces oxidative stress by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.

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Biological Activity

Darirestat (WJ-38) is a small molecule aldose reductase (AR) inhibitor, does not affect AR protein expression, reduces oxidative stress by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.

Physicochemical Properties

M.Wt	392.23
Formula	C19H15Cl2NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1(4H)-Quinolineacetic acid, 3-[(2,3-dichlorophenyl)methyl]-6-methoxy-4-oxo-

References

1. Yang L, et al. Eur J Pharmacol. 2024 Mar 15;967:176376.

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Darirestat (WJ-38)

Biological Activity

Physicochemical Properties

References

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