Chemical Structure : Darovasertib
CAS No.: 1874276-76-2
Catalog No.: PC-38356Not For Human Use, Lab Use Only.
Darovasertib (NVP-LXS196, LXS 196, IDE 196) is a potent, selectve, oral pan- protein kinase C (PKC) inhibitor with IC50 of 3 nM and 0.6 nM for PKCα and PKCθ, respectively.
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M.Wt | 472.47 | |
Formula | C22H23F3N8O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3-amino-N-(3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl)-6-(3-(trifluoromethyl)pyridin-2-yl)pyrazine-2-carboxamide |
1. Ellen Kapiteijn, et al. Cancer Res (2019) 79 (13_Supplement): CT068.
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