Catalog No.: PC-38548Not For Human Use, Lab Use Only.
Debio 0930 (MY 63-78) is a specific and potent direct AMPK activator, allosterically activates AMPK activity in prostate cancer cells with EC50 of 25 uM, without altering the energy levels.
Debio 0930 (MY 63-78) is a specific and potent direct AMPK activator, allosterically activates AMPK activity in prostate cancer cells with EC50 of 25 uM, without altering the energy levels.
MT 63-78 activates AMPK mainly by binding the β1 subunit in a cell-based context, LKB1 is not essential for MT 63-78-mediated activation of AMPK.
MT 63-78 inhibits PCa cell growth and soft agar colony formation, induces mitotic arrest and apoptosis.
MT 63-78 enhances the growth inhibitory effect of AR signaling inhibitors, inhibits tumor growth in xenograft models.
