Decoglurant (RO4995819)

Chemical Structure : Decoglurant

CAS No.: 911115-16-7

Catalog No.: PC-73234Not For Human Use, Lab Use Only.

Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 with antidepressant effect.

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5 mg	$198	In stock
10 mg	$288	In stock
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Biological Activity

Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 with antidepressant effect.

M.Wt	447.34
Formula	C21H11F6N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine

1. Wilkinson ST, et al. Drug Discov Today. 2019 Feb;24(2):606-615.

2. Umbricht D, et al. J Clin Psychiatry. 2020 Jul 14;81(4):18m12470.