Catalog No.: PC-35446Not For Human Use, Lab Use Only.
Dersimelagon (MT-7117) is an orally bioavailable selective, non-peptide melanocortin-1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human, cynomolgus monkey, mouse and rat MC1R, respectively.
Dersimelagon (MT-7117) is an orally bioavailable selective, non-peptide melanocortin-1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human, cynomolgus monkey, mouse and rat MC1R, respectively.
Dersimelagon (MT-7117) shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively.
Dersimelagon (MT-7117) increases eumelanin production in a concentration-dependent manner, with EC50 of 13 pM in B16F1 cells.
