Cat. No. |
Product Name |
Information |
PC-38702 |
CRN04894
MC2R antagonist
|
CRN04894 is a highly potent, selective, orally available melanocortin 2 receptor (MC2R antagonist) antagonist with Ki of 2.1 nM. |
PC-35446 |
Dersimelagon
MC1R agonist
|
Dersimelagon (MT-7117) is an orally bioavailable selective, non-peptide melanocortin-1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human, cynomolgus monkey, mouse and rat MC1R, respectively. |
PC-61573 |
ML00253764
MC4R inhibitor
|
ML00253764 is a non-peptide, brain penetrant melanocortin MC4 receptor (MC4R) antagonist with IC50 of 0.32, 0.81 and 2.12 uM for MC4, MC3 and MC5 receptors, respectively. |
PC-61572 |
BL-6020 979
MC4R antagonist
|
BL-6020/979 (SNT207979) is an orally available, selective, potent MC4R antagonist with IC50 of 19 nM. |
PC-60215 |
BMS-470539
MC-1R agonist
|
BMS-470539 is a potent, selective, full agonist of human and murine melanocortin-1 receptor (MC-1R) with EC50 of 16.8 and 11.6 nM, respectively. |
PC-60214 |
PF-00446687
|
PF-00446687 (PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM. |
PC-60213 |
PF-00446687 hydrochloride
|
PF-00446687 hydrochloride (PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM. |
PC-45520 |
Bremelanotide acetate
|
Bremelanotide acetate is an analogue of the naturally occurring peptide alpha-MSH. |
PC-45743 |
Setmelanotide
Melanocortin receptor agonist
|
Setmelanotide (RM-493, BIM-22493, IRC-022493) is a peptide, non-selective melanocortin receptor agonist with binding Ki of 3.9/10/2.1 for hMC1R/hMC3R/hMC4R, respectively. |
PC-22664 |
JKC-363
MC4R antagonist
|
JKC-363 (JKC363) is a highly potent, selective melanocortin MC4 receptor antagonist with IC50 of 0.5 nM, 90-fold selective over MC3 receptor. |
PC-21480 |
MCL0020
MC4R inverse agonist
|
MCL0020 is a potent, selective inverse agonist of melanocortin MC4 receptor (MC4R) with binding IC50 of 11.6 nM, shows negligible affinity for MC1 and MC3 receptors. |
PC-49762 |
SNT-207707
MC4R inhibitor
|
SNT-207707 (SNT207707) is a potent, selective, BBB-penetrating, and orally active melanocortin-4 (MC-4) receptor antagonist with binding/fuaction IC50 of 8/5 nM, respectively. |