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Chemical Structure : SNT-207858
Catalog No.: PC-49761Not For Human Use, Lab Use Only.
SNT-207858 (SNT207858) is a potent, selective, BBB-penetrating, and orally active melanocortin-4 (MC4R) receptor antagonist with binding/fuaction IC50 of 22/11 nM, respectively.
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SNT-207858 (SNT207858) is a potent, selective, BBB-penetrating, and orally active melanocortin-4 (MC4R) receptor antagonist with binding/fuaction IC50 of 22/11 nM, respectively.
SNT-207858 treatment increase food intake in healthy mice.
SNT-207858 prevented tumor induced weight loss, and diminished loss of lean body mass and fat mass.
| M.Wt | 616.63 | |
| Formula | C32H43Cl2N5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Weyermann P, et al. PLoS One. 2009;4(3):e4774.
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