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Ro 27-3225

Chemical Structure : Ro 27-3225

CAS No.:

Ro 27-3225 (Ro27-3225, Ro 27-3225 trifluoroacetate salt)

Catalog No.: PC-36115Not For Human Use, Lab Use Only.

Ro 27-3225 (Ro27-3225, Ro 27-3225 trifluoroacetate salt) is a potent, selective melanocortin melanocortin receptor MC4R agonist with EC50 of 1 nM, >30-fold selectivity over MC3R.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Ro 27-3225 (Ro27-3225, Ro 27-3225 trifluoroacetate salt) is a potent, selective melanocortin melanocortin receptor MC4R agonist with EC50 of 1 nM, >30-fold selectivity over MC3R.
    Ro 27-3225 shows some activity at the MC1 receptor (EC50=8 nM), reverses hemorrhagic shock, reduces multiple organ damage, and improves survival.

    Physicochemical Properties

    M.Wt 784.91 (free base)
    Formula C41H53F3N12O8
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    References

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