SNT-207707 | MC4R inhibitor | Probechem Biochemicals

Chemical Structure : SNT-207707

SNT-207707 (SNT207707)

Catalog No.: PC-49762Not For Human Use, Lab Use Only.

SNT-207707 (SNT207707) is a potent, selective, BBB-penetrating, and orally active melanocortin-4 (MC-4) receptor antagonist with binding/fuaction IC50 of 8/5 nM, respectively.

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Biological Activity

SNT-207707 (SNT207707) is a potent, selective, BBB-penetrating, and orally active melanocortin-4 (MC-4) receptor antagonist with binding/fuaction IC50 of 8/5 nM, respectively.
SNT-207707 treatment increase food intake in healthy mice.
SNT-207707 prevented tumor induced weight loss, and diminished loss of lean body mass and fat mass.

Physicochemical Properties

M.Wt	550.19
Formula	C32H44ClN5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-cyanophenyl)-N,N-diisopentyl-3-(3-(pyrrolidin-1-yl)propyl)imidazo[1,2-a]pyridine-6-carboxamide hydrochloride

References

1. Weyermann P, et al. PLoS One. 2009;4(3):e4774.

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SNT-207707 (SNT207707)

Biological Activity

Physicochemical Properties

References

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