Chemical Structure : Desidustat
CAS No.: 1616690-16-4
Catalog No.: PC-60509Not For Human Use, Lab Use Only.
Desidustat (ZYAN1) is a novel HIF prolyl hydroxylase (PHD) inhibitor under clinical development for the treatment of anemia.
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Desidustat (ZYAN1) is a novel HIF prolyl hydroxylase (PHD) inhibitor under clinical development for the treatment of anemia.
Desidustat (ZYAN1) increases circulating EPO levels after acute treatment in mice (10.3±3.7 and 40.0±8.5 fold rise at 15 and 30 mg/kg, respectively).
Desidustat (ZYAN1) demonstrates hematinic potential by combined effects on EPO release and efficient iron utilization in nephrectomized rats.
M.Wt | 332.312 | |
Formula | C16H16N2O6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-[1-(cyclopropylmethoxy)-4-hydroxy-2-oxo- 1,2-dihydroquinoline-3-carbonyl]glycine |
1. Jain MR, et al. Drug Res (Stuttg). 2016 Feb;66(2):107-12.
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