Deuruxolitinib | JAK1/2 inhibitor | Probechem Biochemicals

Chemical Structure : Deuruxolitinib

CAS No.: 1513883-39-0

Catalog No.: PC-26217Not For Human Use, Lab Use Only.

Deuruxolitinib is the deuterated form of Ruxolitinib, is an orally active JAK1 and JAK2 inhibitor.

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Biological Activity

Deuruxolitinib is the deuterated form of Ruxolitinib, is an orally active JAK1 and JAK2 inhibitor.

M.Wt	314.42
Formula	C17H10D8N6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-(cyclopentyl-2,2,3,3,4,4,5,5-d8)propanenitrile

1. Brett King, et al. J Am Acad Dermatol. 2024 Nov;91(5):880-888.

2. Barati Sedeh F, et al. Acta Derm Venereol. 2023 Jan 25;103:adv00855.