Chemical Structure : Deutivacaftor
CAS No.: 1413431-07-8
Catalog No.: PC-23052Not For Human Use, Lab Use Only.
Deutivacaftor (VX-561, CTP-656, Ivacaftor-d9) is a potent, orally active CFTR potentiator/modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE.
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Deutivacaftor (VX-561, CTP-656, Ivacaftor-d9) is a potent, orally active CFTR potentiator/modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE.
M.Wt | 401.55 | |
Formula | C24H19D9N2O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(2-(tert-butyl)-5-hydroxy-4-(2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide |
1. Uluer AZ, et al. Lancet Respir Med. 2023 Jun;11(6):550-562.
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