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Chemical Structure : Dexpramipexole dihydrochloride
CAS No.: 104632-27-1
Catalog No.: PC-45174Not For Human Use, Lab Use Only.
A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $240 | In stock |
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A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively; also possesses low/insignificant affinity (500–10,000 nM) for the 5-HT1A, 5-HT1B, 5-HT1D, and α2-adrenergic receptors; used for treating Parkinson's disease (PD) and restless legs syndrome (RLS).
Alzheimer's Disease
Phase 2 Clinical
| M.Wt | 284.249 | |
| Formula | C10H19Cl2N3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 28 mg/mL |
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| Chemical Name/SMILES |
2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, hydrochloride (1:2), (6R)- |
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1. Alavian KN, et al. Brain Res. 2012 Mar 29;1446:1-11.
2. Cudkowicz M, et al. Nat Med. 2011 Nov 20;17(12):1652-6.
3. Bozik ME, et al. J Clin Pharmacol. 2011 Aug;51(8):1177-85.
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