Chemical Structure : Didemnin B
CAS No.: 77327-05-0
Catalog No.: PC-21727Not For Human Use, Lab Use Only.
Didemnin B is selective eukaryotic elongation factor 1A1 (EEF1A1) inhibitor, Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum.
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Didemnin B is selective eukaryotic elongation factor 1A1 (EEF1A1) inhibitor, Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum.
M.Wt | 1112.37 | |
Formula | C57H89N7O15 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(S)-N-((R)-1-(((3S,6R,7S,10R,11S,15S,17S,20S,25aS)-10-((S)-sec-butyl)-11-hydroxy-20-isobutyl-15-isopropyl-3-(4-methoxybenzyl)-2,6,17-trimethyl-1,4,8,13,16,18,21-heptaoxodocosahydro-15H-pyrrolo[2,1-f][1,15]dioxa[4,7,10,20]tetraazacyclotricosin-7-yl)amino)-4-methyl-1-oxopentan-2-yl)-1-((S)-2-hydroxypropanoyl)-N-methylpyrrolidine-2-carboxamide |
1. Stewart JA, et al. Cancer. 1991;68(12):2550-2554.
2. Li LH, et al. Cancer Lett. 1984;23(3):279-288.
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