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Chemical Structure : Dimethylenastron
CAS No.: 863774-58-7
Catalog No.: PC-45755Not For Human Use, Lab Use Only.
Dimethylenastron is a small molecule inhibitor of the mitotic kinesin Eg5.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
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Dimethylenastron is a small molecule inhibitor of the mitotic kinesin Eg5.
Dimethylenastron inhibits endothelial cell proliferation and migration in vitro.
Dimethylenastron exhibits a shorter mitotic arrest, bipolar or multipolar karyokinesis, followed by apoptosis of the daughter cells in dimethylenastron-treated tetraploid cells.
| M.Wt | 302.3913 | |
| Formula | C16H18N2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 31 mg/mL |
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| Chemical Name/SMILES |
5(1H)-Quinazolinone, 2,3,4,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo- |
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1. Rello-Varona S, et al. Cell Cycle. 2009 Apr 1;8(7):1030-5.
2. Exertier P, et al. Oncotarget. 2013 Dec;4(12):2302-16.
3. Kaan HY, et al. J Med Chem. 2010 Aug 12;53(15):5676-83.
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