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Dimethyl fumarate

Chemical Structure : Dimethyl fumarate

CAS No.: 624-49-7

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Dimethyl fumarate (DMF;BG-12)

Catalog No.: PC-45182Not For Human Use, Lab Use Only.

Dimethyl fumarate (DMF, BG-12) exerts anti-inflammatory and pro-metabolic effects in a variety of cell types, activates the Nrf2 pathway.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Dimethyl fumarate (DMF, BG-12) exerts anti-inflammatory and pro-metabolic effects in a variety of cell types, activates the Nrf2 pathway.
Dimethyl fumarate has an effective novel treatment for multiple sclerosis.
Dimethyl fumarate activates the Nrf2 pathway and has been identified as a nicotinic acid receptor agonist in vitro.

Physicochemical Properties

M.Wt 144.1253
Formula C6H8O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 9.6 mg/mL
Chemical Name/SMILES

2-Butenedioic acid (2E)-, 1,4-dimethyl ester

References

1. Peng H, et al. J Biol Chem. 2012 Aug 10;287(33):28017-26.

2. Ashrafian H, et al. Cell Metab. 2012 Mar 7;15(3):361-71.

3. Scannevin RH, et al. J Pharmacol Exp Ther. 2012 Apr;341(1):274-84.

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