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Chemical Structure : Dipraglurant
CAS No.: 872363-17-2
Catalog No.: PC-49069Not For Human Use, Lab Use Only.
Dipraglurant (ADX48621) is a negative allosteric modulator (NAM) of metabotropic glutamate 5 (mGlu5) receptor with IC50 of 21 nM.
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|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $368 | In stock | |
| 25 mg | $588 | In stock | |
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Dipraglurant (ADX48621) is a negative allosteric modulator (NAM) of metabotropic glutamate 5 (mGlu5) receptor with IC50 of 21 nM.
Dipraglurant (ADX48621) shows potential for the treatment of Parkinson's disease levodopa-induced dyskinesia (PD-LID).
| M.Wt | 265.291 | |
| Formula | C16H12FN3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
6-fluoro-2-(4-pyridin-2-ylbut-3-ynyl)imidazo[1,2-a]pyridine |
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1. Sciamanna G, et al. Neuropharmacology. 2014 Oct;85:440-50.
2. Pourmirbabaei S, et al. Eur J Pharmacol. 2019 Jul 15;855:149-159.
3. Bezard E, et al. Mov Disord. 2014 Jul;29(8):1074-9.
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