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Chemical Structure : Diprovocim-X
Catalog No.: PC-47088Not For Human Use, Lab Use Only.
Diprovocim-X is a potent human and murine TLR1/TLR2 agonist with EC50 of 0.14 nM (hTLR1/TLR2) and 0.75 nM (m TLR1/TLR2), respectively.
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Diprovocim-X is a potent human and murine TLR1/TLR2 agonist with EC50 of 0.14 nM (hTLR1/TLR2) and 0.75 nM (m TLR1/TLR2), respectively.
Diprovocim-X exhibits the excellent potency/efficacy of diprovocim-1 in human cells, displays substantially improved potency/efficacy in mouse macrophages, and serves as an adjuvant in mice when coadministered with a nonimmunogenic antigen.
| M.Wt | 1134.429 | |
| Formula | C66H83N7O10 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ming-Hsiu Yang, et al. J Med Chem. 2022 Jun 29. doi: 10.1021/acs.jmedchem.2c00419.
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