E104 | TLR7 agonist | Probechem Biochemicals

Chemical Structure : E104

Catalog No.: PC-21155Not For Human Use, Lab Use Only.

E014 is a potent, selective TLR7 agonist with EC50 of 69 nM in Ramos Blue reporter assays, >500-fold selective for TLR7 over TLR8.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

E014 is a potent, selective TLR7 agonist with EC50 of 69 nM in Ramos Blue reporter assays, >500-fold selective for TLR7 over TLR8.

M.Wt	345.45
Formula	C21H23N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-aminobenzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine

1. Emma G. DeYoung, et al. ACS Medicinal Chemistry Letters 2023