EC134 (EC-134)

Chemical Structure : EC134

Catalog No.: PC-28035Not For Human Use, Lab Use Only.

EC134 is a potent, cell-active small-molecule inhibitor of CBX7 with IC50 of 34 uM in FP assays, inhibits viability of OCI-AML3 with IC50 of 22 uM.

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Biological Activity

EC134 is a potent, cell-active small-molecule inhibitor of CBX7 with IC50 of 34 uM in FP assays, inhibits viability of OCI-AML3 with IC50 of 22 uM.

Physicochemical Properties

M.Wt	430.55
Formula	C26H30N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-(5-(2,6-dimethylphenyl)-6-methylpyridin-2-yl)piperazine-1-carbonyl)-1-ethylpyridin-2(1H)-one

References

1. Chelsea R Wilson, et al. RSC Med Chem. 2026 Aug 7. doi: 10.1039/d6md00215c.

2. Anne P de Groot, et al. Blood Neoplasia. 2024 Oct 24;1(4):100052.

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EC134 (EC-134)

Biological Activity

Physicochemical Properties

References

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