Chemical Structure : EC330
CAS No.: 2016795-77-8
Catalog No.: PC-42293Not For Human Use, Lab Use Only.
EC330 (EC-330, EC 330) is a first-in-class, orally bioavailable LIF (leukemia inhibitory factor) inhibitor.
Packing | Price | Stock | Quantity |
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5 mg | $198 | In stock | |
10 mg | $298 | In stock | |
25 mg | $498 | In stock | |
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EC330 (EC-330, EC 330) is a first-in-class, orally bioavailable LIF (leukemia inhibitory factor) inhibitor.
EC330 shows cytotoxicity in various cancer cell line and NCI-60 cell line panel at low nano-molar range; reduces tumor burden in ovarian (IGROV-1) and triple negative breast cancer (MDA-MB-231) cell xenografted mouse models as well as MDA-MB-231 PDX models; orally bioavailable.
M.Wt | 462.5706864 | |
Formula | C30H32F2O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Estra-4,9-dien-3-one, 11-(4-cyclopropylphenyl)-17-(1,1-difluoro-2-propyn-1-yl)-17-hydroxy-, (11β,17β)- |
1. Nair HB, et al. Discovery and preclinical pharmacology of EC330: A first-in-class leukemia inhibitory factor (LIF) inhibitor.
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