EC5026 | sEH inhibitor | Probechem Biochemicals

Chemical Structure : EC5026

CAS No.: 1809885-32-2

EC5026 (EC 5026, BPN-19186)

Catalog No.: PC-21825Not For Human Use, Lab Use Only.

EC5026 (BPN-19186) is a potent, selective orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 0.04 nM, shows potential for the treatment of neuropathic pain.

Packing	Price	Stock
5 mg	$78	In stock
10 mg	$118	In stock
25 mg	$188	In stock
50 mg	$288	In stock
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Biological Activity

EC5026 (BPN-19186) is a potent, selective orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 0.04 nM, shows potential for the treatment of neuropathic pain.

Physicochemical Properties

M.Wt	405.39
Formula	C18H23F4N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-3-(1-(2-methylbutanoyl)piperidin-4-yl)urea

References

1. Abigail G Kelly, et al. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2314085121.

2. Hammock BD, et al. J Med Chem. 2021 Feb 25;64(4):1856-1872.

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EC5026 (EC 5026, BPN-19186)

Biological Activity

Physicochemical Properties

References

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