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EC5026

Chemical Structure : EC5026

CAS No.: 1809885-32-2

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EC5026 (EC 5026, BPN-19186)

Catalog No.: PC-21825Not For Human Use, Lab Use Only.

EC5026 (BPN-19186) is a potent, selective orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 0.04 nM, shows potential for the treatment of neuropathic pain.

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10 mg $58 In stock
25 mg $98 In stock
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100 mg $258 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

EC5026 (BPN-19186) is a potent, selective orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 0.04 nM, shows potential for the treatment of neuropathic pain.

Physicochemical Properties

M.Wt 405.39
Formula C18H23F4N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-3-(1-(2-methylbutanoyl)piperidin-4-yl)urea

References

1. Abigail G Kelly, et al. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2314085121.

2. Hammock BD, et al. J Med Chem. 2021 Feb 25;64(4):1856-1872.

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