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EDV33

Chemical Structure : EDV33

CAS No.: 3034671-41-2

EDV33

Catalog No.: PC-22948Not For Human Use, Lab Use Only.

EDV33 is a potent, non-selective inhibitor of ADAMTSs with Ki app value of 68, 31, 6.5, 4.3 and 4.0 nM for ADAMTS-7, ADAMTS-4, ADAMTS-5, ADAM-17 and MMP-2 respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

EDV33 is a potent, non-selective inhibitor of ADAMTSs with Ki app value of 68, 31, 6.5, 4.3 and 4.0 nM for ADAMTS-7, ADAMTS-4, ADAMTS-5, ADAM-17 and MMP-2 respectively.

Physicochemical Properties

M.Wt 550.00
Formula C25H25ClFN3O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-N-(4-((4-((2-chloro-4-fluorobenzyl)oxy)phenyl)sulfonamido)-5-(hydroxyamino)-5-oxopentyl)benzamide

References

1. Salvatore Santamaria, et al. J Enzyme Inhib Med Chem. 2021 Dec;36(1):2160-2169.

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