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Chemical Structure : EG00229 free base
CAS No.: 1018927-63-3
Catalog No.: PC-35130Not For Human Use, Lab Use Only.
EG00229 is a specific inhibitor of neuropilin-1 (NRP1)/VEGF-A interaction, inhibits the binding of biotinylated VEGFA to NRP1 with IC50 of 8 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $348 | In stock | |
| 50 mg | $558 | In stock | |
| 100 mg | Get quote |
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EG00229 is a specific inhibitor of neuropilin-1 (NRP1)/VEGF-A interaction, inhibits the binding of biotinylated VEGFA to NRP1 with IC50 of 8 uM.
EG00229 also demonstrates to have functional effects on cell-migration and VEGF-R2 phosphorylation.
| M.Wt | 497.563 | |
| Formula | C17H19N7O5S3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)thiophene-2-carboxamido)-5-((diaminomethylene)amino)pentanoic acid |
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1. Powell J, et al. J Med Chem. 2018 May 10;61(9):4135-4154.
2. Jarvis A, et al. J Med Chem. 2010 Mar 11;53(5):2215-26.
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