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ELOVL1-IN-2

Chemical Structure : ELOVL1-IN-2

CAS No.: 2761063-79-8

ELOVL1-IN-2

Catalog No.: PC-26755Not For Human Use, Lab Use Only.

ELOVL1-IN-2 is a specific ELOVL1 inhibitor with IC50 of 21 μM, inhibits the condensation step of fatty acid elongation and reduces the synthesis of very long-chain fatty acids, including C26:0 VLCFA.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ELOVL1-IN-2 is a specific ELOVL1 inhibitor with IC50 of 21 μM, inhibits the condensation step of fatty acid elongation and reduces the synthesis of very long-chain fatty acids, including C26:0 VLCFA.

Physicochemical Properties

M.Wt 294.33
Formula C18H15FN2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(4-fluorophenethoxy)-3,3'-bipyridine

References

1. Boyd MJ, et al. Discovery of Novel, Orally Bioavailable Pyrimidine Ether-Based Inhibitors of ELOVL1. J Med Chem. 2021;64(24):17777-17794.

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