ELQ-596 | Antiparasite | Probechem Biochemicals

Chemical Structure : ELQ-596

ELQ-596 (ELQ596)

Catalog No.: PC-22513Not For Human Use, Lab Use Only.

ELQ-596 is a endochin-like quinolone compound with potent antibabesial activity with IC50 of 32 nM against B. duncani in human erythrocytes.

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Biological Activity

ELQ-596 is a endochin-like quinolone compound with potent antibabesial activity with IC50 of 32 nM against B. duncani in human erythrocytes.
ELQ-596 display no cytotoxity against human cell lines: HeLa, HepG2, HEK293, and HCT116 (IC50>10 uM).

Physicochemical Properties

M.Wt	459.85
Formula	C24H17ClF3NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-chloro-7-methoxy-2-methyl-3-(4'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)quinolin-4(3H)-one

References

1. Pratap Vydyam, et al. ACS Infect Dis. 2024 Apr 12;10(4):1405-1413.

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ELQ-596 (ELQ596)

Biological Activity

Physicochemical Properties

References

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