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ELQ-596

Chemical Structure : ELQ-596

CAS No.: 3023709-98-7

ELQ-596 (ELQ596)

Catalog No.: PC-22513Not For Human Use, Lab Use Only.

ELQ-596 is a endochin-like quinolone compound with potent antibabesial activity with IC50 of 32 nM against B. duncani in human erythrocytes.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ELQ-596 is a endochin-like quinolone compound with potent antibabesial activity with IC50 of 32 nM against B. duncani in human erythrocytes.
ELQ-596 display no cytotoxity against human cell lines: HeLa, HepG2, HEK293, and HCT116 (IC50>10 uM).

Physicochemical Properties

M.Wt 459.85
Formula C24H17ClF3NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-chloro-7-methoxy-2-methyl-3-(4'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)quinolin-4(3H)-one

References

1. Pratap Vydyam, et al. ACS Infect Dis. 2024 Apr 12;10(4):1405-1413.

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