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EML405

Chemical Structure : EML405

CAS No.: 2101954-79-2

EML405 (EML-405, EML 405)

Catalog No.: PC-70162Not For Human Use, Lab Use Only.

EML405 (EML 405) is a small-molecule inhibitor of the methyl-lysine reader protein Spindlin1 (SPIN1) with Kd of 14 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    EML405 (EML 405) is a small-molecule inhibitor of the methyl-lysine reader protein Spindlin1 (SPIN1) with Kd of 14 uM.
    EML405 shows novel interaction with the Tudor-domain-containing protein Spindlin1 (SPIN1).

    Physicochemical Properties

    M.Wt 585.837
    Formula C36H51N5O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (2-(phenylamino)-1,4-phenylene)bis((4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)methanone)

    References

    1. Bae N, et al. Nat Chem Biol. 2017 May 15. doi: 10.1038/nchembio.2377.

    2. Wang W, et al. EMBO Rep. 2011 Oct 28;12(11):1160-6.

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