EML405 | SPIN1 inhibitor | ProbeChem Biochemicals

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Chemical Structure : EML405

EML405 (EML-405, EML 405)

Catalog No.: PC-70162Not For Human Use, Lab Use Only.

EML405 (EML 405) is a small-molecule inhibitor of the methyl-lysine reader protein Spindlin1 (SPIN1) with Kd of 14 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

EML405 (EML 405) is a small-molecule inhibitor of the methyl-lysine reader protein Spindlin1 (SPIN1) with Kd of 14 uM.
EML405 shows novel interaction with the Tudor-domain-containing protein Spindlin1 (SPIN1).

Physicochemical Properties

M.Wt	585.837
Formula	C36H51N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(2-(phenylamino)-1,4-phenylene)bis((4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)methanone)

References

1. Bae N, et al. Nat Chem Biol. 2017 May 15. doi: 10.1038/nchembio.2377.

2. Wang W, et al. EMBO Rep. 2011 Oct 28;12(11):1160-6.

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EML405 (EML-405, EML 405)

Biological Activity

Physicochemical Properties

References

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