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Chemical Structure : ENMD-2076
CAS No.: 934353-76-1
Catalog No.: PC-42766Not For Human Use, Lab Use Only.
ENMD-2076 is a multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
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ENMD-2076 is a multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2, respectively.
ENMD-2076 also inhibits Aurora B, c-Kit, FGFR1 (IC50=100-350 nM).
ENMD-2076 is orally bioactive.
| M.Wt | 375.4701 | |
| Formula | C21H25N7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-Pyrimidinamine, 6-(4-methyl-1-piperazinyl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(1E)-2-phenylethenyl]- |
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1. Tentler JJ, et al. Clin Cancer Res. 2010 Jun 1;16(11):2989-98.
2. Matulonis UA, et al. Eur J Cancer. 2013 Jan;49(1):121-31.
3. Fletcher GC, et al. Mol Cancer Ther. 2011 Jan;10(1):126-37.
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