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EPZ033294

Chemical Structure : EPZ033294

CAS No.: 1887195-17-6

EPZ033294 (EPZ 033294)

Catalog No.: PC-21040Not For Human Use, Lab Use Only.

EPZ033294 is a potent, selective inhibitor of SMYD2 with biochemical IC50 of 3.9 nM, and function of cellular methylation IC50 of 29 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

EPZ033294 is a potent, selective inhibitor of SMYD2 with biochemical IC50 of 3.9 nM, and function of cellular methylation IC50 of 29 nM.

Physicochemical Properties

M.Wt 411.89
Formula C20H22ClN7O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(C1=CN(C2CC2)N=N1)NC3CN(CC4=CN(CC5=CC=C(Cl)C=C5)N=C4)C3

References

1. Michael J Thomenius, et al. PLoS One. 2018 Jun 1;13(6):e0197372.

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