EPZ033294 | SMYD2 inhibitor | Probechem Biochemicals

Chemical Structure : EPZ033294

Catalog No.: PC-21040Not For Human Use, Lab Use Only.

EPZ033294 is a potent, selective inhibitor of SMYD2 with biochemical IC50 of 3.9 nM, and function of cellular methylation IC50 of 29 nM.

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Biological Activity

EPZ033294 is a potent, selective inhibitor of SMYD2 with biochemical IC50 of 3.9 nM, and function of cellular methylation IC50 of 29 nM.

M.Wt	411.89
Formula	C20H22ClN7O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(C1=CN(C2CC2)N=N1)NC3CN(CC4=CN(CC5=CC=C(Cl)C=C5)N=C4)C3

1. Michael J Thomenius, et al. PLoS One. 2018 Jun 1;13(6):e0197372.