Chemical Structure : ER-27319 maleate
CAS No.: 1204480-26-1
Catalog No.: PC-61632Not For Human Use, Lab Use Only.
ER-27319 maleate is a potent, selective inhibitor of antigen or anti-IgE-mediated degranulation of rodent and human mast cells by selective inhibition of FcɛRI-mediated activation of Syk.
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ER-27319 maleate is a potent, selective inhibitor of antigen or anti-IgE-mediated degranulation of rodent and human mast cells by selective inhibition of FcɛRI-mediated activation of Syk.
ER-27319 does not inhibits the anti-CD3-induced tyrosine phosphorylation of phospholipase C-gamma1 in Jurkat T cells.
M.Wt | 396.17 | |
Formula | C18H20N2O.C4H4O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate |
1. Moriya K, et al. Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12539-44.
2. Andrews RP, et al. J Leukoc Biol. 2001 Nov;70(5):776-82.
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