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ER-27319 maleate

Chemical Structure : ER-27319 maleate

CAS No.: 1204480-26-1

ER-27319 maleate (ER27319 maleate)

Catalog No.: PC-61632Not For Human Use, Lab Use Only.

ER-27319 maleate is a potent, selective inhibitor of antigen or anti-IgE-mediated degranulation of rodent and human mast cells by selective inhibition of FcɛRI-mediated activation of Syk.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ER-27319 maleate is a potent, selective inhibitor of antigen or anti-IgE-mediated degranulation of rodent and human mast cells by selective inhibition of FcɛRI-mediated activation of Syk.
ER-27319 does not inhibits the anti-CD3-induced tyrosine phosphorylation of phospholipase C-gamma1 in Jurkat T cells.

Physicochemical Properties

M.Wt 396.17
Formula C18H20N2O.C4H4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate

References

1. Moriya K, et al. Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12539-44.

2. Andrews RP, et al. J Leukoc Biol. 2001 Nov;70(5):776-82.

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