ER 50891 | RARα inhibitor | Probechem Biochemicals

Chemical Structure : ER-50891

CAS No.: 187400-85-7

Catalog No.: PC-20200Not For Human Use, Lab Use Only.

ER-50891 (ER50891) is a potent, selective antagonist of RARα receptor with IC50 of 31.2 nM, displays >300-fold selectivity over RARγ and RARβ.

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Biological Activity

ER-50891 (ER50891) is a potent, selective antagonist of RARα receptor with IC50 of 31.2 nM, displays >300-fold selectivity over RARγ and RARβ.

M.Wt	432.52
Formula	C29H24N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(5-(8-isopropyl-4-phenylquinolin-2-yl)-1H-pyrrol-2-yl)benzoic acid

1. K Kikuchi, et al. Bioorg Med Chem Lett. 2001 May 7;11(9):1215-8.