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ER-50891

Chemical Structure : ER-50891

CAS No.: 187400-85-7

ER-50891 (ER50891)

Catalog No.: PC-20200Not For Human Use, Lab Use Only.

ER-50891 (ER50891) is a potent, selective antagonist of RARα receptor with IC50 of 31.2 nM, displays >300-fold selectivity over RARγ and RARβ.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ER-50891 (ER50891) is a potent, selective antagonist of RARα receptor with IC50 of 31.2 nM, displays >300-fold selectivity over RARγ and RARβ.

Physicochemical Properties

M.Wt 432.52
Formula C29H24N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(5-(8-isopropyl-4-phenylquinolin-2-yl)-1H-pyrrol-2-yl)benzoic acid

References

1. K Kikuchi, et al. Bioorg Med Chem Lett. 2001 May 7;11(9):1215-8.

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