Catalog No.: PC-72983Not For Human Use, Lab Use Only.
ES9-17 is a non-protonophoric, improved Endosidin9 (ES9) analog that inhibits clathrin heavy chain (CHC) function in both Arabidopsis and human cells, inhibits clathrin-mediated endocytosis (CME).
ES9-17 is a non-protonophoric, improved Endosidin9 (ES9) analog that inhibits clathrin heavy chain (CHC) function in both Arabidopsis and human cells, inhibits clathrin-mediated endocytosis (CME).
ES9-17 inhibits transferrin uptake in HeLa cells with EC50 of 17.2 uM.
ES9-17 inhibits clathrin heavy chain (CHC) function in both Arabidopsis and human cells through affinity-based target isolation in vitro binding studies.
Physicochemical Properties
M.Wt
318.203
Formula
C10H8BrNO2S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
5-bromo-N-phenylthiophene-2-sulfonamide
References
1. Dejonghe W, et al. Nat Chem Biol. 2019 Jun;15(6):641-649.
2. Dejonghe W, et al. Nat Commun. 2016 Jun 8;7:11710.
