| Cat. No. |
Product Name |
Information |
| PC-72983 |
ES9-17
Clathrin inhibitor
|
ES9-17 is a non-protonophoric, improved Endosidin9 (ES9) analog that inhibits clathrin heavy chain (CHC) function in both Arabidopsis and human cells, inhibits clathrin-mediated endocytosis (CME). |
| PC-72982 |
Endosidin 9
Endocytosis inhibitor
|
Endosidin 9 (ES9) is a novel mitochondrial uncoupler, and a potent inhibitor of clathrin-mediated endocytosis (CME) in different systems, strongly reduces FM4-64 uptake in Arabidopsis root cells with IC50 of 5 uM. |
| PC-72007 |
Wbox2
Clathrin inhibitor peptide
|
Wbox2 is a membrane-permeant peptide that potently inhibits clathrin-mediated endocytosis (CME, IC50=3 uM), binds to SNX9 and AP2 and perturbs clathrin interactions with AP2 and SNX9. |
| PC-35161 |
AK306
Clathrin inhibitor
|
AK306 is a small molecule clathrin heavy chain (CLTC/CHC) binding compound that induces arrest and apoptosis of the HCT116 colon cancer cell line with EC50 of 50 nM. |
| PC-60190 |
Pitstop 2
Endocytosis inhibitor
|
Pitstop 2 is a small molecule inhibitor of clathrin terminal domain and inhibits clathrin-mediated endocytosis. |
| PC-60189 |
Pitstop 1
Endocytosis inhibitor
|
A potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM (inhibition of clathrin TD-amphiphysin B/C complex formation). |
