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Chemical Structure : Endosidin 9
Catalog No.: PC-72982Not For Human Use, Lab Use Only.
Endosidin 9 (ES9) is a novel mitochondrial uncoupler, and a potent inhibitor of clathrin-mediated endocytosis (CME) in different systems, strongly reduces FM4-64 uptake in Arabidopsis root cells with IC50 of 5 uM.
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Endosidin 9 (ES9) is a novel mitochondrial uncoupler, and a potent inhibitor of clathrin-mediated endocytosis (CME) in different systems, strongly reduces FM4-64 uptake in Arabidopsis root cells with IC50 of 5 uM.
Endosidin 9 (ES9) inhibits CME dynamics and organelle movement in the cytoplasm.
Endosidin9 (ES9) inhibits clathrin-mediated endocytosis largely through cytoplasmic acidification.
| M.Wt | 363.2 | |
| Formula | C10H7BrN2O4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dejonghe W, et al. Nat Chem Biol. 2019 Jun;15(6):641-649.
2. Dejonghe W, et al. Nat Commun. 2016 Jun 8;7:11710.
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